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BIOSTATISTICS & RESEARCH METHODOLOGY
This is a topic-wise Biostatistics & Research Methodology IV PharmD notes according to the Syllabus Prescribed by PCI. This notes will help in the preparation & revision of the subject during exam time. I welcome any kind of suggestion and feedback for further development of the notes.
TOPICS
RESEARCH METHODOLOGY
1. Types of Clinical Study Designs
2. Designing the Methodology
3. Sample Size Determination & Power of a Study
4. Report Writing & Presentation of Data
BIOSTATISTICS
5. Introduction
6. Types of Data Distribution
7. Measures of Central Tendency- Average/ Mean, Median, Mode
8. Measurement of the spread of data range, variation of mean, standard deviation, variance, coefficient of variation, standard error of mean
DATA GRAPHICS
9. Construction & Labeling of graphs, histogram, pie charts, scatter plots, semi-logarithimic plots
BASICS OF TESTING HYPOTHESIS
10. Null Hypothesis, Level of Significance, Power of test, P value, statistical estimation of confidence intervals
11. Level of significance (Parametric Data)- students t test, chi square test, Analysis of Variance
12. Level of significance (Non- parametric Data)- sign test, Wilcoxan's signed rank test, Wilcoxan rank sum test, Mann Whitney U test, Kruskal- Wall test
13. Linear regression and correlation- Introduction, Pearson's and Spearmann's correlation and correlation coefficient
14. Introduction to statistical software: SPSSS, Epi info, SAS
BASICS OF TESTING HYPOTHESIS- NUMERICAL
STATISTICAL METHODS IN EPIDEMIOLOGY
15. Incidence and prevalence, relative risk, attributable risk
16. COMPUTER APPLICATIONS IN PHARMACY
Note: The above notes are only for preparation & revision of subject during exams. They cannot substitue the deep knowledge present in the textbooks.
Biostatistics & Research Methodology Textbooks recommended by RGUHS
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Pharmaceutical statistics- practical and clinical applications, Stanford Bolton 3rd edition
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Drug Information- A Guide for Pharmacists, Patrick M Malone, Karen L Kier, John E Stanovich, 3rd edition, McGraw Hill publications 2006
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